Jason Biggs peed on Chelsea Handler face.

What a pal! Chelsea Handler sat down with Conan O'Brien on Wednesday, Oct. 15, and retold a gross story about that time when her buddy Jason Biggs peed on her face.

"There's this horrifying video on the web," O'Brien noted of actress Jenny Mollen's viral Vine from last month involving the American Pie actor and comedienne. "Jason Biggs is standing on what appears to be a dock, and there's no other way to say it…. He's urinating on you. I had to bring it up because I think we need an explanation."